Development of Tumor Cell-Based Vaccine with IL-12 Gene Electrotransfer as Adjuvant

Tumor cell-based vaccines use tumor cells as a source of tumor-associated antigens. In our study, we aimed to develop and test a tumor vaccine composed of tumor cells killed by irradiation combined with in vivo interleukin-12 gene electrotransfer as an adjuvant. Vaccination was performed in the skin...

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Bibliographic Details
Main Authors: Tinkara Remic, Gregor Sersa, Katja Ursic, Maja Cemazar, Urska Kamensek
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/1/111