mTOR Inhibitor Therapy and Metabolic Consequences: Where Do We Stand?

mTOR (mechanistic target of rapamycin) protein kinase acts as a central integrator of nutrient signaling pathways. Besides the immunosuppressive role after solid organ transplantations or in the treatment of some cancers, another promising role of mTOR inhibitor as an antiaging therapeutic has emerg...

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Bibliographic Details
Main Authors: Aleksandra Kezic, Ljiljana Popovic, Katarina Lalic
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/2640342