Concept Study for an Integrated Reactor-Crystallizer Process for the Continuous Biocatalytic Synthesis of (<i>S</i>)-1-(3-Methoxyphenyl)ethylamine

An integrated biocatalysis-crystallization concept was developed for the continuous amine transaminase-catalyzed synthesis of (<i>S</i>)-1-(3-methoxyphenyl)ethylamine, which is a valuable intermediate for the synthesis of rivastigmine, a highly potent drug for the treatment of early stag...

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Bibliographic Details
Main Authors: Dennis Hülsewede, Erik Temmel, Peter Kumm, Jan von Langermann
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/10/5/345