ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues
Abstract High-throughput RNA-sequencing (RNA-seq) technologies provide an unprecedented opportunity to explore the individual transcriptome. Unmapped reads are a large and often overlooked output of standard RNA-seq analyses. Here, we present Read Origin Protocol (ROP), a tool for discovering the so...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
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Series: | Genome Biology |
Online Access: | http://link.springer.com/article/10.1186/s13059-018-1403-7 |