Tumor microenvironment affects exogenous sodium/iodide symporter expression
For decades, sodium/iodide symporter NIS-mediated iodide uptake has played a crucial role in the radioactive ablation of thyroid cancer cells. NIS-based gene therapy has also become a promising tool for the treatment of tumors of extrathyroidal origin. But its applicability has been hampered by redu...
Main Authors: | Fabio Castillo-Rivera, Alejandro Ondo-Méndez, Julien Guglielmi, Jean-Marie Guigonis, Lun Jing, Sabine Lindenthal, Andrea Gonzalez, Diana López, Béatrice Cambien, Thierry Pourcher |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Translational Oncology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1936523320304290 |
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