Protective microbiomes can limit the evolution of host pathogen defense

Abstract The evolution of host immunity occurs in the context of the microbiome, but little theory exists to predict how resistance against pathogens might be influenced by the need to tolerate and regulate commensal microbiota. We present a general model to explore the optimal investment in host im...

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Bibliographic Details
Main Authors: C. Jessica E. Metcalf, Britt Koskella
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Evolution Letters
Subjects:
Online Access:https://doi.org/10.1002/evl3.140