Wolbachia transcription elongation factor "Wol GreA" interacts with α2ββ'σ subunits of RNA polymerase through its dimeric C-terminal domain.

Wolbachia transcription elongation factor "Wol GreA" interacts with α2ββ'σ subunits of RNA polymerase through its dimeric C-terminal domain.

OBJECTIVES: Wolbachia, an endosymbiont of filarial nematode, is considered a promising target for therapy against lymphatic filariasis. Transcription elongation factor GreA is an essential factor that mediates transcriptional transition from abortive initiation to productive elongation by stimulatin...

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Bibliographic Details
Main Authors: Jeetendra Kumar Nag, Nidhi Shrivastava, Dhanvantri Chahar, Chhedi Lal Gupta, Preeti Bajpai, Shailja Misra-Bhattacharya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4063747?pdf=render

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http://europepmc.org/articles/PMC4063747?pdf=render

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