Tumor Acidity as Evolutionary Spite

Most cancer cells shift their metabolic pathway from a metabolism reflecting the Pasteur-effect into one reflecting the Warburg-effect. This shift creates an acidic microenvironment around the tumor and becomes the driving force for a positive carcinogenesis feedback loop. As a consequence of tumor...

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Bibliographic Details
Main Authors: Mohammed E. A. Shayoub, Khalid O. Alfarouk, Abdel Khalig Muddathir
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/1/408/