Porphyromonas gingivalis regulates TREM-1 in human polymorphonuclear neutrophils via its gingipains.

The Triggering Receptor Expressed on Myeloid cells 1 (TREM-1) is a cell surface receptor of the immunoglobulin superfamily, with the capacity to amplify pro-inflammatory cytokine production and regulate apoptosis. Polymorphonuclear neutrophils (PMNs) are the first line of defence against infection,...

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Bibliographic Details
Main Authors: Nagihan Bostanci, Thomas Thurnheer, Joseph Aduse-Opoku, Michael A Curtis, Annelies S Zinkernagel, Georgios N Belibasakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790815?pdf=render