Modulation of Adenosine-Induced Responses in the Guinea-Pig Trachea During Long-Term Caffeine Treatment: Possible Role of Epithelium

The responses to adenosine were studied on isolated, methacholine-precontracted tracheal strips of guinea pigs in the course of long-term caffeine or solvent treatment. Guinea pigs were fed caffeine for 10 weeks (average serum caffeine concentration: 39.1 ± 3.9 µM). In epithelium-intact tracheal pre...

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Bibliographic Details
Main Authors: László Brugós, Rudolf Gesztelyi, Judit Zsuga, Ágnes Cseppento, Ilona Benko, Zoltán Galajda, György Deák, Sándor Sipka, Tamás Roszer, Péter Kovács, Mária Szilasi, István Édes, András József Szentmiklósi
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319341933