Promise of Neoadjuvant Immunotherapy in Resected Non-small Cell Lung Cancer

Promise of Neoadjuvant Immunotherapy in Resected Non-small Cell Lung Cancer

Immune checkpoint inhibitor (ICI) has been proven to be a major breakthrough in patients with advanced non-small cell lung cancer. Up to now, neoadjuvant therapy using ICI are rare. However, in the context of cancer immunotherapy, neoadjuvant treatment may offer an extra advantage. In this review, w...

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Main Authors: Shuyang YAO, Yi ZHANG
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2020-01-01
Series:Chinese Journal of Lung Cancer
Subjects:
lung neoplasms
local advanced stage
neoadjuvant therapy
immunotherapy
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2020.01.09
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spelling doaj-d667f2c827664ada91860d108c82085a2020-11-25T02:06:37ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872020-01-01231555910.3779/j.issn.1009-3419.2020.01.09Promise of Neoadjuvant Immunotherapy in Resected Non-small Cell Lung CancerShuyang YAO0Yi ZHANG1Department of Thoracic Surgery, Xuanwu Hospital, Diagnostic and Treatment Centers of Lung Cancer, Capital Medical University, Beijing 100053, ChinaDepartment of Thoracic Surgery, Xuanwu Hospital, Diagnostic and Treatment Centers of Lung Cancer, Capital Medical University, Beijing 100053, ChinaImmune checkpoint inhibitor (ICI) has been proven to be a major breakthrough in patients with advanced non-small cell lung cancer. Up to now, neoadjuvant therapy using ICI are rare. However, in the context of cancer immunotherapy, neoadjuvant treatment may offer an extra advantage. In this review, we will disscuss the existing preclinical data and emerging clinical findings in the neoadjuvant setting and its potential mechanism of action. We will also highlight the potential damage and the questions that are required to be answered.http://dx.doi.org/10.3779/j.issn.1009-3419.2020.01.09lung neoplasmslocal advanced stageneoadjuvant therapyimmunotherapy
collection DOAJ
language zho
format Article
sources DOAJ
author Shuyang YAO
Yi ZHANG
spellingShingle Shuyang YAO
Yi ZHANG
Promise of Neoadjuvant Immunotherapy in Resected Non-small Cell Lung Cancer
Chinese Journal of Lung Cancer
lung neoplasms
local advanced stage
neoadjuvant therapy
immunotherapy
author_facet Shuyang YAO
Yi ZHANG
author_sort Shuyang YAO
title Promise of Neoadjuvant Immunotherapy in Resected Non-small Cell Lung Cancer
title_short Promise of Neoadjuvant Immunotherapy in Resected Non-small Cell Lung Cancer
title_full Promise of Neoadjuvant Immunotherapy in Resected Non-small Cell Lung Cancer
title_fullStr Promise of Neoadjuvant Immunotherapy in Resected Non-small Cell Lung Cancer
title_full_unstemmed Promise of Neoadjuvant Immunotherapy in Resected Non-small Cell Lung Cancer
title_sort promise of neoadjuvant immunotherapy in resected non-small cell lung cancer
publisher Chinese Anti-Cancer Association; Chinese Antituberculosis Association
series Chinese Journal of Lung Cancer
issn 1009-3419
1999-6187
publishDate 2020-01-01
description Immune checkpoint inhibitor (ICI) has been proven to be a major breakthrough in patients with advanced non-small cell lung cancer. Up to now, neoadjuvant therapy using ICI are rare. However, in the context of cancer immunotherapy, neoadjuvant treatment may offer an extra advantage. In this review, we will disscuss the existing preclinical data and emerging clinical findings in the neoadjuvant setting and its potential mechanism of action. We will also highlight the potential damage and the questions that are required to be answered.
topic lung neoplasms
local advanced stage
neoadjuvant therapy
immunotherapy
url http://dx.doi.org/10.3779/j.issn.1009-3419.2020.01.09
work_keys_str_mv AT shuyangyao promiseofneoadjuvantimmunotherapyinresectednonsmallcelllungcancer
AT yizhang promiseofneoadjuvantimmunotherapyinresectednonsmallcelllungcancer
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