Nonintegrating Direct Conversion Using mRNA into Hepatocyte-Like Cells

Recently, several researchers have reported that direct reprogramming techniques can be used to differentiate fibroblasts into hepatocyte-like cells without a pluripotent intermediate step. However, the use of viral vectors for conversion continues to pose important challenges in terms of genome int...

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Bibliographic Details
Main Authors: Sangtae Yoon, Kyojin Kang, Young-duck Cho, Yohan Kim, Elina Maria Buisson, Ji-Hye Yim, Seung Bum Lee, Ki-Young Ryu, Jaemin Jeong, Dongho Choi
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/8240567