Comparison of the Mini Mental State Examination and depressive symptoms between high cardiovascular risk and healthy community elderly groups

• Main Authors: Amanda Lucas da Costa, Juliana Santos Varela, Osmar Mazetti, Luciane Restelatto, Andry Fitterman Costa, Claudia Godinho, Ana Luiza Camozzato, Paulo D. Picon, Márcia L. Chaves
• Format: Article
• Language: English
• Published: Associação Neurologia Cognitiva e do Comportamento
• Series: Dementia & Neuropsychologia
• Subjects: cognitive disorder; cardiovascular risk; Mini Mental State Examination; depressive disorders.
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642008000400294&lng=en&tlng=en

Abstract The aging of the population is a universal phenomenon with direct consequences upon the public health system. One of the main repercussions of the growth in this sector of the population is the increased prevalence of disorders such as dementia and depression which are very frequent among the elderly. The relationship between cardiovascular risk factors, dementia and depression have been addressed in many recent investigations. Objectives: To evaluate the relationship of cognitive performance and depressive symptoms with cardiovascular risk in the elderly. Methods: 94 high cardiovascular risk elderly patients and 160 healthy community elderly were evaluated cross-sectionally. The Mini Mental State Examination (MMSE) and the Geriatric Depression Scale (GDS-15) were used as the main measures. The cutoff for presence of depression was 6 on the GDS. Results: The high cardiovascular risk elderly group showed significantly lower scores on the MMSE (p<0.001) and was significantly associated to depression (p<0.001), independently of education. The logistic regression analysis for depression as the dependent variable, age and group (healthy community or high cardiovascular risk elderly) were kept in the final equation. Higher age (Odds Ratio=0.92; 95% CI 0.86-0.98) and high cardiovascular risk elderly (OR=2.99; 95% CI 1.36-6.59) were associated to depression. Conclusions: The present findings corroborate the different cognitive performance of elderly with high cardiovascular risk factors and the association of depressive symptoms with this group.