Spontaneous emergence of multiple drug resistance in tuberculosis before and during therapy.

The emergence of drug resistance in M. tuberculosis undermines the efficacy of tuberculosis (TB) treatment in individuals and of TB control programs in populations. Multiple drug resistance is often attributed to sequential functional monotherapy, and standard initial treatment regimens have therefo...

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Bibliographic Details
Main Authors: Caroline Colijn, Ted Cohen, Ayalvadi Ganesh, Megan Murray
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3068161?pdf=render