Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells.

Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells.

The type 2 transmembrane serine protease matriptase is under tight control primarily by the actions of the integral membrane Kunitz-type serine protease inhibitor HAI-1. Growing evidence indicates that HAI-2 might also be involved in matriptase inhibition in some contexts. Here we showed that matrip...

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Bibliographic Details
Main Authors: Hsiang-Hua D Chang, Yuan Xu, Hongyu Lai, Xiaoyu Yang, Chun-Che Tseng, Ying-Jung J Lai, Yu Pan, Emily Zhou, Michael D Johnson, Jehng-Kang Wang, Chen-Yong Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364774?pdf=render

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http://europepmc.org/articles/PMC4364774?pdf=render

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