KLRG1 and CD103 Expressions Define Distinct Intestinal Tissue-Resident Memory CD8 T Cell Subsets Modulated in Crohn's Disease

KLRG1 and CD103 Expressions Define Distinct Intestinal Tissue-Resident Memory CD8 T Cell Subsets Modulated in Crohn's Disease

Intestinal tissue-resident memory CD8 T cells (Trm) are non-recirculating effector cells ideally positioned to detect and react to microbial infections in the gut mucosa. There is an emerging understanding of Trm cell differentiation and functions, but their implication in inflammatory bowel disease...

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Bibliographic Details
Main Authors: Hugo Bottois, Marjolaine Ngollo, Nassim Hammoudi, Tristan Courau, Julie Bonnereau, Victor Chardiny, Céline Grand, Brice Gergaud, Matthieu Allez, Lionel Le Bourhis
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
T cells
IBD – inflammatory bowel diseases
Crohn's disease
TRM cells
CD103
KLRG1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00896/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00896/full

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