Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome

Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome

In all domains of life, the catalysed degradation of RNA facilitates rapid adaptation to changing environmental conditions, while destruction of foreign RNA is an important mechanism to prevent host infection. We have identified a virus-encoded protein termed gp37/Dip, which directly binds and inhib...

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Bibliographic Details
Main Authors: An Van den Bossche, Steven W Hardwick, Pieter-Jan Ceyssens, Hanne Hendrix, Marleen Voet, Tom Dendooven, Katarzyna J Bandyra, Marc De Maeyer, Abram Aertsen, Jean-Paul Noben, Ben F Luisi, Rob Lavigne
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-07-01
Series:eLife
Subjects:
Pseudomonas aeruginosa
RNA degradosome
bacteriophage
protein-protein interactions
RNA metabolism
Online Access:https://elifesciences.org/articles/16413

Internet

https://elifesciences.org/articles/16413

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