Canonical WNT pathway is activated in the airway epithelium in chronic obstructive pulmonary disease

Canonical WNT pathway is activated in the airway epithelium in chronic obstructive pulmonary disease

Background: Chronic obstructive pulmonary disease (COPD) is a devastating lung disease, mainly due to cigarette smoking, which represents the third cause of mortality worldwide. The mechanisms driving its epithelial salient features remain largely elusive. We aimed to evaluate the activation and the...

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Bibliographic Details
Main Authors: François M. Carlier, Sébastien Dupasquier, Jérôme Ambroise, Bruno Detry, Marylène Lecocq, Charline Biétry–Claudet, Yassine Boukala, Jean-Luc Gala, Caroline Bouzin, Stijn E. Verleden, Delphine Hoton, Sophie Gohy, Bertrand Bearzatto, Charles Pilette
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:EBioMedicine
Subjects:
COPD
WNT
β-catenin
Airway epithelium
Barrier dysfunction
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420304102

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http://www.sciencedirect.com/science/article/pii/S2352396420304102

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