Stable redox-cycling nitroxide Tempol inhibits NET formation

To prevent the spread of pathogens neutrophils as the first line of defence are able to release Neu-trophil Extracellular Traps (NETs), a recently discovered form of immune response. Reactive oxygen species (ROS) have been shown to be essential for many different induction routes of NET formation. T...

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Bibliographic Details
Main Authors: Ava eHosseinzadeh, Philipp Karl Messer, Constantin Felix Urban
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00391/full