Effect of Prooxidative Natural Products: Comparison of the OSI1 (YKL071w) Promoter Luciferase Construct from Yeast with an Nrf2/Keap Reporter System

The oxidative stress response (OSR) in yeast is under the control of oxidation-sensitive cysteines in the Yap1p transcription factor, and fusion of the Yap1p-dependent OS-induced promoter of the <i>YKL071w</i> gene (<i>OSI1</i>) to a luciferase coding sequence makes a sensiti...

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Bibliographic Details
Main Authors: Ivan Schlembach, Andreas Uebachs, Tim Caspers, Athanassios Fragoulis, Alan J. Slusarenko, Martin C. H. Gruhlke
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/10/10/3520