Iso-Oncotic Albumin Mitigates Brain and Kidney Injury in Experimental Focal Ischemic Stroke

Background: There is widespread debate regarding the use of albumin in ischemic stroke. We tested the hypothesis that an iso-oncotic solution of albumin (5%), administered earlier after acute ischemic stroke (3 h), could provide neuroprotection without causing kidney damage, compared to a hyper-onco...

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Main Authors: Renata de S. Mendes, Gloria Martins, Milena V. Oliveira, Nazareth N. Rocha, Fernanda F. Cruz, Mariana A. Antunes, Soraia C. Abreu, Adriana L. Silva, Christina Takiya, Pedro M. Pimentel-Coelho, Chiara Robba, Rosália Mendez-Otero, Paolo Pelosi, Patricia R. M. Rocco, Pedro L. Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Neurology
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Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.01001/full