Identification and transfer of spatial transcriptomics signatures for cancer diagnosis

Identification and transfer of spatial transcriptomics signatures for cancer diagnosis

Abstract Background Distinguishing ductal carcinoma in situ (DCIS) from invasive ductal carcinoma (IDC) regions in clinical biopsies constitutes a diagnostic challenge. Spatial transcriptomics (ST) is an in situ capturing method, which allows quantification and visualization of transcriptomes in ind...

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Bibliographic Details
Main Authors: Niyaz Yoosuf, José Fernández Navarro, Fredrik Salmén, Patrik L. Ståhl, Carsten O. Daub
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Breast Cancer Research
Subjects:
Spatial transcriptomics
Expression signature
Cancer diagnosis
Breast cancer
Machine learning
Online Access:https://doi.org/10.1186/s13058-019-1242-9

Internet

https://doi.org/10.1186/s13058-019-1242-9

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