Elevated glutamatergic compounds in pregenual anterior cingulate in pediatric autism spectrum disorder demonstrated by 1H MRS and 1H MRSI.

Recent research in autism spectrum disorder (ASD) has aroused interest in anterior cingulate cortex and in the neurometabolite glutamate. We report two studies of pregenual anterior cingulate cortex (pACC) in pediatric ASD. First, we acquired in vivo single-voxel proton magnetic resonance spectrosco...

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Bibliographic Details
Main Authors: Anthony Bejjani, Joseph O'Neill, John A Kim, Andrew J Frew, Victor W Yee, Ronald Ly, Christina Kitchen, Noriko Salamon, James T McCracken, Arthur W Toga, Jeffry R Alger, Jennifer G Levitt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3407186?pdf=render