Nerfin-1 represses transcriptional output of Hippo signaling in cell competition

Nerfin-1 represses transcriptional output of Hippo signaling in cell competition

The Hippo tumor suppressor pathway regulates tissue growth in Drosophila by restricting the activity of the transcriptional coactivator Yorkie (Yki), which normally complexes with the TEF/TEAD family DNA-binding transcription factor Scalloped (Sd) to drive the expression of growth-promoting genes. G...

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Bibliographic Details
Main Authors: Pengfei Guo, Chang-Hyun Lee, Huiyan Lei, Yonggang Zheng, Katiuska Daniela Pulgar Prieto, Duojia Pan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-03-01
Series:eLife
Subjects:
Hippo signaling
cell competition
transcription factors
Online Access:https://elifesciences.org/articles/38843

Internet

https://elifesciences.org/articles/38843

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