A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network

Using a variety of technical approaches, we have detected the presence of continuous triads that cover the entire length of T tubules in the main white body muscles of several small fish. This is in contrast to the discontinuous association of SR with T tubules in the red muscles from the same fish...

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Main Authors: Manuela Lavorato, Ramesh Iyer, Clara Franzini-Armstrong
Format: Article
Language:English
Published: PAGEPress Publications 2019-05-01
Series:European Journal of Translational Myology
Subjects:
Online Access:https://www.pagepressjournals.org/index.php/bam/article/view/8264
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spelling doaj-d94b9a8079514a07851ba7d971d839532020-11-24T20:54:36ZengPAGEPress PublicationsEuropean Journal of Translational Myology2037-74522037-74602019-05-0129210.4081/ejtm.2019.8264A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse networkManuela Lavorato0Ramesh Iyer1Clara Franzini-Armstrong2Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PADivision of Cardiology, Children Hospital of Philadelphia, Philadelphia, PADepartment of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA Using a variety of technical approaches, we have detected the presence of continuous triads that cover the entire length of T tubules in the main white body muscles of several small fish. This is in contrast to the discontinuous association of SR with T tubules in the red muscles from the same fish as well as in all other previously described muscles in a large variety of skeletal muscles. We suggest that continuous triads are permissible only in muscle fibers that are not normally subject to significant changes in sarcomere length during normal in vivo activity, as is the case for white muscles in the trunk of fish. https://www.pagepressjournals.org/index.php/bam/article/view/8264UltrastructureSarcoplasmic reticulumTransverse tubulesTriads
collection DOAJ
language English
format Article
sources DOAJ
author Manuela Lavorato
Ramesh Iyer
Clara Franzini-Armstrong
spellingShingle Manuela Lavorato
Ramesh Iyer
Clara Franzini-Armstrong
A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network
European Journal of Translational Myology
Ultrastructure
Sarcoplasmic reticulum
Transverse tubules
Triads
author_facet Manuela Lavorato
Ramesh Iyer
Clara Franzini-Armstrong
author_sort Manuela Lavorato
title A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network
title_short A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network
title_full A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network
title_fullStr A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network
title_full_unstemmed A proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network
title_sort proposed role for non-junctional transverse tubules in skeletal muscle as flexible segments allowing expansion of the transverse network
publisher PAGEPress Publications
series European Journal of Translational Myology
issn 2037-7452
2037-7460
publishDate 2019-05-01
description Using a variety of technical approaches, we have detected the presence of continuous triads that cover the entire length of T tubules in the main white body muscles of several small fish. This is in contrast to the discontinuous association of SR with T tubules in the red muscles from the same fish as well as in all other previously described muscles in a large variety of skeletal muscles. We suggest that continuous triads are permissible only in muscle fibers that are not normally subject to significant changes in sarcomere length during normal in vivo activity, as is the case for white muscles in the trunk of fish.
topic Ultrastructure
Sarcoplasmic reticulum
Transverse tubules
Triads
url https://www.pagepressjournals.org/index.php/bam/article/view/8264
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