Estimation of Ionized Calcium and Corrected Total Calcium Concentration Based on Serum Albumin Level

• Main Authors: Rodica Căpriță, Adrian Caprita, Iuliana Cretescu
• Format: Article
• Language: English
• Published: Agroprint Timisoara 2013-05-01
• Series: Scientific Papers Animal Science and Biotechnologies
• Subjects: albumin; corrected total calcium; ionized calcium; total calcium
• Online Access: http://spasb.ro/index.php/spasb/article/view/216

Ionized calcium is the physiologically active fraction of serum calcium and therefore its evaluation is an important clinical parameter both in mammals and birds. In the present study, concentration of total calcium (tCa), ionized calcium (iCa) based on the serum albumin level and on the total protein content, and corrected total calcium (ctCa) based on the serum albumin level were evaluated, and the correlation between these biochemical parameters was investigated in broiler chickens. The average serum iCa was 4.91±0.49g/dL representing 51.76±0.53% from the ctCa. The correlation coefficient between tCa and albumin (r = 0.8608) was greater than that between tCa and total protein (r = 0.7997). Our study illustrated that iCa and ctCa concentrations calculated from tCa and albumin are better indicators of calcium homeostasis than tCa concentrations alone.