Structural basis for the homotypic fusion of chlamydial inclusions by the SNARE-like protein IncA

Structural basis for the homotypic fusion of chlamydial inclusions by the SNARE-like protein IncA

Chlamydia trachomatis forms membrane-bound inclusions inside the host cell that are decorated with IncA, a SNARE-like protein that promotes the fusion of inclusions. Here, Cingolani et al. show that the protein folds into a non-canonical four-helix bundle and identify an intramolecular clamp require...

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Bibliographic Details
Main Authors: Gino Cingolani, Michael McCauley, Anna Lobley, Alexander J. Bryer, Jordan Wesolowski, Deanna L. Greco, Ravi K. Lokareddy, Erik Ronzone, Juan R. Perilla, Fabienne Paumet
Format: Article
Language:English
Published: Nature Publishing Group 2019-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10806-9

Internet

https://doi.org/10.1038/s41467-019-10806-9

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