No seasonal accumulation of resistant P. falciparum when high-dose chloroquine is used.
Potentially chloroquine resistant P. falciparum, identified by the 76T haplotype in the chloroquine resistance transporter (pfcrt 76T), are highly prevalent throughout Africa. In Guinea-Bissau, normal and double dose chloroquine have respective efficacies of 34% and 78% against P.falciparum with pfc...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-08-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2729929?pdf=render |