Sensitization of Erythrocytes to Suicidal Erythrocyte Death Following Water Deprivation

Sensitization of Erythrocytes to Suicidal Erythrocyte Death Following Water Deprivation

Background/Aims: Klotho deficiency results in excessive formation of 1,25(OH)2D3, accelerated ageing and early death. Moreover, klotho deficiency enhances eryptosis, the suicidal erythrocyte death characterized by phosphatidylserine exposure at the erythrocyte surface. Triggers of eryptosis include...

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Bibliographic Details
Main Authors: Majed Abed, Martina Feger, Kousi Alzoubi, Tatsiana Pakladok, Leonie Frauenfeld, Corinna Geiger, Syeda T Towhid, Florian Lang
Format: Article
Language:English
Published: Karger Publishers 2013-11-01
Series:Kidney & Blood Pressure Research
Subjects:
Eryptosis
Energy depletion
Hyperosmotic shock
Oxidative stress
Ionomycin
Online Access:http://www.karger.com/Article/FullText/355737

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