Role of Ubiquitylation in Controlling Suppressor of Cytokine Signalling 3 (SOCS3) Function and Expression

The realisation that unregulated activation of the Janus kinase–signal transducer and activator of transcription (JAK–STAT) pathway is a key driver of a wide range of diseases has identified its components as targets for therapeutic intervention by small molecule inhibitors and biologicals. In this...

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Bibliographic Details
Main Authors: Jamie J. L. Williams, Kirsten M. A. Munro, Timothy M. Palmer
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Cells
Subjects:
JAK
Online Access:http://www.mdpi.com/2073-4409/3/2/546