Understanding the Mechanisms of Resistance in <em>EGFR</em>-Positive NSCLC: From Tissue to Liquid Biopsy to Guide Treatment Strategy

Understanding the Mechanisms of Resistance in <em>EGFR</em>-Positive NSCLC: From Tissue to Liquid Biopsy to Guide Treatment Strategy

Liquid biopsy has emerged as an alternative source of nucleic acids for the management of Epidermal Growth Factor Receptor (<i>EGFR</i>)-mutant non-Small Cell Lung Cancer (NSCLC). The use of circulating cell-free DNA (cfDNA) has been recently introduced in clinical practice, resulting in...

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Bibliographic Details
Main Authors: Marzia Del Re, Stefania Crucitta, Giulia Gianfilippo, Antonio Passaro, Iacopo Petrini, Giuliana Restante, Angela Michelucci, Stefano Fogli, Filippo de Marinis, Camillo Porta, Antonio Chella, Romano Danesi
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
liquid biopsy
epidermal growth factor receptor
non-Small Cell Lung Cancer
circulating cell-free DNA
tyrosine kinase inhibitors
mechanisms of resistance
Online Access:https://www.mdpi.com/1422-0067/20/16/3951

Internet

https://www.mdpi.com/1422-0067/20/16/3951

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