The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer.

The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer.

Quantifying chromosomal instability (CIN) has both prognostic and predictive clinical utility in breast cancer. In order to establish a robust and clinically applicable gene expression-based measure of CIN, we assessed the ability of four qPCR quantified genes selected from the 70-gene Chromosomal I...

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Bibliographic Details
Main Authors: Attila Marcell Szász, Qiyuan Li, Aron C Eklund, Zsófia Sztupinszki, Andrew Rowan, Anna-Mária Tőkés, Borbála Székely, András Kiss, Miklós Szendrői, Balázs Győrffy, Zoltán Szállási, Charles Swanton, Janina Kulka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3582639?pdf=render

Internet

http://europepmc.org/articles/PMC3582639?pdf=render

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