A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans

Abstract Context Multiple observational studies have reported an inverse relationship between 25-hydroxyvitamin D concentrations (25(OH)D) and type 2 diabetes (T2D). However, the results of short- and long-term interventional trials concerning the relationship between 25(OH)D and T2D risk have been...

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Main Authors: Cynthia A. Bejar, Shiwali Goyal, Shoaib Afzal, Massimo Mangino, Ang Zhou, Peter J. van der Most, Yanchun Bao, Vipin Gupta, Melissa C. Smart, Gagandeep K. Walia, Niek Verweij, Christine Power, Dorairaj Prabhakaran, Jai Rup Singh, Narinder K. Mehra, Gurpreet S. Wander, Sarju Ralhan, Sanjay Kinra, Meena Kumari, Martin H. de Borst, Elina Hyppönen, Tim D. Spector, Børge G. Nordestgaard, Piers R. Blackett, Dharambir K. Sanghera
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Nutrition Journal
Online Access:https://doi.org/10.1186/s12937-021-00725-1