Conjugates of Small Molecule Drugs with Antibodies and Other Proteins

Conjugates of small molecule drugs with antibodies (ADCs) and with other proteins (protein-drug conjugates, PDC) are used as a new class of targeted therapeutics combining the specificity of monoclonal antibodies (mAbs) and other proteins with potent cytotoxic activity of small molecule drugs for th...

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Bibliographic Details
Main Authors: Yang Feng, Zhongyu Zhu, Weizao Chen, Ponraj Prabakaran, Kedan Lin, Dimiter S. Dimitrov
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Biomedicines
Subjects:
ADC
Online Access:http://www.mdpi.com/2227-9059/2/1/1