A Single δ9-Tetrahydrocannabinol (THC) Dose During Brain Development Affects Markers of Neurotrophy, Oxidative Stress, and Apoptosis

A Single δ9-Tetrahydrocannabinol (THC) Dose During Brain Development Affects Markers of Neurotrophy, Oxidative Stress, and Apoptosis

δ9-tetrahydrocannabinol (THC) is one of the most used drugs during pregnancy and lactation and efficiently crosses the placental and blood–brain barriers. Despite the recent legalization initiatives worldwide, the adverse outcome pathway (AOP) of THC following exposure during brain development is in...

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Bibliographic Details
Main Authors: Gaëtan Philippot, Erica Forsberg, Caroline Tahan, Henrik Viberg, Robert Fredriksson
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
Subjects:
δ9-tetrahydrocannabinol
developmental toxicology and neurotoxicology
acetaminophen (paracetamol)
Trkb
oxidative stress
brain growth spurt
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01156/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01156/full

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