Effects of Brain-Derived Neurotrophic Factor on Local Inflammation in Experimental Stroke of Rat

This study was aimed to investigate whether brain-derived neurotrophic factor (BDNF) can modulate local cerebral inflammation in ischemic stroke. Rats were subjected to ischemia by occluding the right middle cerebral artery (MCAO) for 2 hours. Rats were randomized as control, BDNF, and antibody grou...

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Bibliographic Details
Main Authors: Yongjun Jiang, Ning Wei, Juehua Zhu, Tingting Lu, Zhaoyao Chen, Gelin Xu, Xinfeng Liu
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2010/372423