Molecular analysis of the endobronchial stent microbial biofilm reveals bacterial communities that associate with stent material and frequent fungal constituents.

Endobronchial stents are increasingly used to treat airway complications in multiple conditions including lung transplantation but little is known about the biofilms that form on these devices. We applied deep sequencing to profile luminal biofilms of 46 endobronchial stents removed from 20 subjects...

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Bibliographic Details
Main Authors: John E McGinniss, Ize Imai, Aurea Simon-Soro, Melanie C Brown, Vincent R Knecht, Laura Frye, Priyanka M Ravindran, Marisol I Dothard, Dylan A Wadell, Michael B Sohn, Hongzhe Li, Jason D Christie, Joshua M Diamond, Andrew R Haas, Anthony R Lanfranco, David M DiBardino, Frederic D Bushman, Ronald G Collman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0217306