Evaluation of peripapillary retinal nerve fiber layer thickness in myopic children

AIM:To evaluation the retinal nerve fiber layer(RNFL)thickness in children from 4~10 years associated with myopia.<p>METHODS:Forty Chinese children between 4 and 10 years of age in our hospital from January 2012 to May 2014 were selected as test subjects. Patients whose manifest refraction mea...

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Main Authors: Yong-Yu Yao, Hong-Hui Xia, Wei Fan, Cong-Yi Li
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-06-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2015/6/201506046.pdf
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spelling doaj-dbd9757ac5d54c329717013e126538a82020-11-25T01:11:49ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232015-06-011561097109910.3980/j.issn.1672-5123.2015.6.46Evaluation of peripapillary retinal nerve fiber layer thickness in myopic childrenYong-Yu Yao0Hong-Hui Xia1Wei Fan2Cong-Yi Li3Department of Ophthalmology, Gaoyao People's Hospital, Gaoyao 526100, Guangdong Province, ChinaDepartment of Ophthalmology, Gaoyao People's Hospital, Gaoyao 526100, Guangdong Province, ChinaDepartment of Ophthalmology, Gaoyao People's Hospital, Gaoyao 526100, Guangdong Province, ChinaDepartment of Ophthalmology, Gaoyao People's Hospital, Gaoyao 526100, Guangdong Province, ChinaAIM:To evaluation the retinal nerve fiber layer(RNFL)thickness in children from 4~10 years associated with myopia.<p>METHODS:Forty Chinese children between 4 and 10 years of age in our hospital from January 2012 to May 2014 were selected as test subjects. Patients whose manifest refraction measurement values ranged 0D≤diopter<-3.00D were classified as low myopia group(14 cases), those -3.00D≤diopter<-6.00D were classified as moderate myopia group(14 cases), and those ≥-6.00D were classified as high myopia group(12 cases). RNFL thickness was measured by time-domain optical coherence tomography(OCT: Stratus OCT; Carl Zeiss Meditec)for every subject.<p>RESULTS:The average RNFL thicknesses were 102.36±10.33μm in high myopia group, 112.66±9.79μm in low myopia group and 106.52±9.46μm in moderate myopia group. A statistically significant difference was found between high myopia and low myopia groups(<i>P</i><0.05). There was no statistically significant difference found neither between high myopia and mild myopia groups, nor between moderate myopia and low myopia groups(<i>P</i>>0.05). In addition, RNFL thickness was decrease especially in the inferior quadrant in children with high myopia and moderate myopia compared with low myopia groups(<i>P</i><0.05). <p>CONCLUSION:The average RNFL thickness is significantly thinner in high myopic children relative to low myopic children. And, the average RNFL thickness of inferior quadrant is significantly thinner in high myopic and moderate myopia children relative to low myopic children. Therefore, when interpreting OCT results of RNFL thickness in the clinic, more attention should be given to changes associated with myopia.http://ies.ijo.cn/cn_publish/2015/6/201506046.pdfchildrenmyopiaretinal nerve fiber layer
collection DOAJ
language English
format Article
sources DOAJ
author Yong-Yu Yao
Hong-Hui Xia
Wei Fan
Cong-Yi Li
spellingShingle Yong-Yu Yao
Hong-Hui Xia
Wei Fan
Cong-Yi Li
Evaluation of peripapillary retinal nerve fiber layer thickness in myopic children
Guoji Yanke Zazhi
children
myopia
retinal nerve fiber layer
author_facet Yong-Yu Yao
Hong-Hui Xia
Wei Fan
Cong-Yi Li
author_sort Yong-Yu Yao
title Evaluation of peripapillary retinal nerve fiber layer thickness in myopic children
title_short Evaluation of peripapillary retinal nerve fiber layer thickness in myopic children
title_full Evaluation of peripapillary retinal nerve fiber layer thickness in myopic children
title_fullStr Evaluation of peripapillary retinal nerve fiber layer thickness in myopic children
title_full_unstemmed Evaluation of peripapillary retinal nerve fiber layer thickness in myopic children
title_sort evaluation of peripapillary retinal nerve fiber layer thickness in myopic children
publisher Press of International Journal of Ophthalmology (IJO PRESS)
series Guoji Yanke Zazhi
issn 1672-5123
1672-5123
publishDate 2015-06-01
description AIM:To evaluation the retinal nerve fiber layer(RNFL)thickness in children from 4~10 years associated with myopia.<p>METHODS:Forty Chinese children between 4 and 10 years of age in our hospital from January 2012 to May 2014 were selected as test subjects. Patients whose manifest refraction measurement values ranged 0D≤diopter<-3.00D were classified as low myopia group(14 cases), those -3.00D≤diopter<-6.00D were classified as moderate myopia group(14 cases), and those ≥-6.00D were classified as high myopia group(12 cases). RNFL thickness was measured by time-domain optical coherence tomography(OCT: Stratus OCT; Carl Zeiss Meditec)for every subject.<p>RESULTS:The average RNFL thicknesses were 102.36±10.33μm in high myopia group, 112.66±9.79μm in low myopia group and 106.52±9.46μm in moderate myopia group. A statistically significant difference was found between high myopia and low myopia groups(<i>P</i><0.05). There was no statistically significant difference found neither between high myopia and mild myopia groups, nor between moderate myopia and low myopia groups(<i>P</i>>0.05). In addition, RNFL thickness was decrease especially in the inferior quadrant in children with high myopia and moderate myopia compared with low myopia groups(<i>P</i><0.05). <p>CONCLUSION:The average RNFL thickness is significantly thinner in high myopic children relative to low myopic children. And, the average RNFL thickness of inferior quadrant is significantly thinner in high myopic and moderate myopia children relative to low myopic children. Therefore, when interpreting OCT results of RNFL thickness in the clinic, more attention should be given to changes associated with myopia.
topic children
myopia
retinal nerve fiber layer
url http://ies.ijo.cn/cn_publish/2015/6/201506046.pdf
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