Optimizing Vancomycin Dosing in Chronic Kidney Disease by Deriving and Implementing a Web-Based Tool Using a Population Pharmacokinetics Analysis

Background: Chronic kidney disease (CKD) patients requiring intravenous vancomycin bear considerable risks of adverse outcomes both from the infection and vancomycin therapy itself, necessitating especially precise dosing to avoid sub- and supratherapeutic vancomycin exposure.Methods: In this retros...

Full description

Bibliographic Details
Main Authors: Sreemanee Raaj Dorajoo, Chrystal Leandra Winata, Jessica Hui Fen Goh, Say Tat Ooi, Jyoti Somani, Lee Ying Yeoh, Siok Ying Lee, Chun Wei Yap, Alexandre Chan, Jung-woo Chae
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00641/full