Autoantibodies Against Ubiquitous and Confined Antigens in Patients With Ocular, Neuro-Ophthalmic and Congenital Cerebral Toxoplasmosis

Autoantibodies Against Ubiquitous and Confined Antigens in Patients With Ocular, Neuro-Ophthalmic and Congenital Cerebral Toxoplasmosis

Toxoplasma gondii infection can trigger autoreactivity by different mechanisms. In the case of ocular toxoplasmosis, disruption of the blood-retinal barrier may cause exposure of confined retinal antigens such as recoverin. Besides, cross-reactivity can be induced by molecular mimicry of parasite an...

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Bibliographic Details
Main Authors: Monica Goldberg-Murow, Carlos Cedillo-Peláez, Luz Elena Concha-del-Río, Rashel Cheja-Kalb, María José Salgar-Henao, Eduardo Orozco-Velasco, Héctor Luna-Pastén, Fernando Gómez-Chávez, Antonio Ibarra, Dolores Correa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
Toxoplasma gondii
ocular toxoplasmosis
autoantibodies
HSP70
recoverin
hippocalcin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.606963/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.606963/full

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