Anti-parasitic effect of vitamin C alone and in combination with benznidazole against Trypanosoma cruzi.

BACKGROUND:Drugs currently used for the treatment of Chagas' disease, nifurtimox and benznidazole, have a limited effectiveness and toxic side effects. With the aim of finding new therapeutic approaches, in vitro and in vivo anti-Trypanosoma cruzi activity of vitamin C alone and combined with b...

Full description

Bibliographic Details
Main Authors: Vanesa Puente, Agostina Demaria, Fernanda M Frank, Alcira Batlle, Maria Elisa Lombardo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6169970?pdf=render