Division of labour between PP2A-B56 isoforms at the centromere and kinetochore
PP2A-B56 is a serine/threonine phosphatase complex that regulates several major mitotic processes, including sister chromatid cohesion, kinetochore-microtubule attachment and the spindle assembly checkpoint. We show here that these key functions are divided between different B56 isoforms that locali...
Main Authors: | Giulia Vallardi, Lindsey A Allan, Lisa Crozier, Adrian T Saurin |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-03-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/42619 |
Similar Items
-
Molecular basis of outer kinetochore assembly on CENP-T
by: Pim J Huis in 't Veld, et al.
Published: (2016-12-01) -
The pseudo GTPase CENP-M drives human kinetochore assembly
by: Federica Basilico, et al.
Published: (2014-07-01) -
The centromere comes into focus: from CENP-A nucleosomes to kinetochore connections with the spindle
by: Kathryn Kixmoeller, et al.
Published: (2020-06-01) -
Network of protein interactions within the Drosophila inner kinetochore
by: Magdalena M. Richter, et al.
Published: (2016-01-01) -
Reconstitution reveals two paths of force transmission through the kinetochore
by: Grace E Hamilton, et al.
Published: (2020-05-01)