A condensation-ordering mechanism in nanoparticle-catalyzed peptide aggregation.

Nanoparticles introduced in living cells are capable of strongly promoting the aggregation of peptides and proteins. We use here molecular dynamics simulations to characterise in detail the process by which nanoparticle surfaces catalyse the self-assembly of peptides into fibrillar structures. The s...

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Bibliographic Details
Main Authors: Stefan Auer, Antonio Trovato, Michele Vendruscolo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19680431/pdf/?tool=EBI