Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation.

BACKGROUND: Pathogenic yersiniae inject several effector proteins (Yops) into host cells, which subverts immune functions and enables the bacteria to survive within the host organism. YopM, whose deletion in enteropathogenic yersiniae results in a dramatic loss of virulence, has previously been show...

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Bibliographic Details
Main Authors: Moritz Hentschke, Laura Berneking, Cristina Belmar Campos, Friedrich Buck, Klaus Ruckdeschel, Martin Aepfelbacher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2950144?pdf=render