Osteitis Fibrosa Cystica Mistaken for Malignant Disease
A 65-year-old man with back pain had plain radiographs that showed multiple osteolytic bone lesions of the pelvis, femur and L-spine; an magnetic resonance imaging scan of the L-spine showed extensive bony resorption with a posterior epidural mass involving the L1 spinous process; these findings sug...
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Korean Society of Otorhinolaryngology-Head and Neck Surgery
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Online Access: | http://www.e-ceo.org/upload/pdf/ceo-6-110.pdf |
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doaj-dccf5ea118cd4473a3cfa62008c9c1602020-11-24T21:15:43ZengKorean Society of Otorhinolaryngology-Head and Neck SurgeryClinical and Experimental Otorhinolaryngology1976-87102005-07202013-06-016211011310.3342/ceo.2013.6.2.110232Osteitis Fibrosa Cystica Mistaken for Malignant DiseaseJa Hyun Lee0Sung Min Chung1Han Su Kim2Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.Department of Otolaryngology and Head & Neck Surgery, Ewha Womans University School of Medicine, Seoul, Korea.Department of Otolaryngology and Head & Neck Surgery, Ewha Womans University School of Medicine, Seoul, Korea.A 65-year-old man with back pain had plain radiographs that showed multiple osteolytic bone lesions of the pelvis, femur and L-spine; an magnetic resonance imaging scan of the L-spine showed extensive bony resorption with a posterior epidural mass involving the L1 spinous process; these findings suggested multiple myeloma or bony metastasis. However, all serology testing was negative. The parathyroid hormone and serum calcium levels were found to be abnormally elevated. A fine needle aspiration biopsy suggested that the L-spine lesion was consistent with the diagnosis of osteitis fibrosa cystica. A pathological fracture of the spine compressed the spinal cord, and surgical intervention was required. The neck computed tomography and Tc-99m sestamibi scan showed a solitary parathyroid mass. A minimally invasive parathyroidectomy using intraoperative parathyroid hormone monitoring was performed and two enlarged parathyroid glands identified. This case illustrates the importance of the consideration of a rare brown tumor associated with primary hyperparathyroidism in patients with the bone lesions suggestive of a malignancy.http://www.e-ceo.org/upload/pdf/ceo-6-110.pdfHyperparathyroidismOsteitis fibrosa cysticaBrown tumor |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ja Hyun Lee Sung Min Chung Han Su Kim |
spellingShingle |
Ja Hyun Lee Sung Min Chung Han Su Kim Osteitis Fibrosa Cystica Mistaken for Malignant Disease Clinical and Experimental Otorhinolaryngology Hyperparathyroidism Osteitis fibrosa cystica Brown tumor |
author_facet |
Ja Hyun Lee Sung Min Chung Han Su Kim |
author_sort |
Ja Hyun Lee |
title |
Osteitis Fibrosa Cystica Mistaken for Malignant Disease |
title_short |
Osteitis Fibrosa Cystica Mistaken for Malignant Disease |
title_full |
Osteitis Fibrosa Cystica Mistaken for Malignant Disease |
title_fullStr |
Osteitis Fibrosa Cystica Mistaken for Malignant Disease |
title_full_unstemmed |
Osteitis Fibrosa Cystica Mistaken for Malignant Disease |
title_sort |
osteitis fibrosa cystica mistaken for malignant disease |
publisher |
Korean Society of Otorhinolaryngology-Head and Neck Surgery |
series |
Clinical and Experimental Otorhinolaryngology |
issn |
1976-8710 2005-0720 |
publishDate |
2013-06-01 |
description |
A 65-year-old man with back pain had plain radiographs that showed multiple osteolytic bone lesions of the pelvis, femur and L-spine; an magnetic resonance imaging scan of the L-spine showed extensive bony resorption with a posterior epidural mass involving the L1 spinous process; these findings suggested multiple myeloma or bony metastasis. However, all serology testing was negative. The parathyroid hormone and serum calcium levels were found to be abnormally elevated. A fine needle aspiration biopsy suggested that the L-spine lesion was consistent with the diagnosis of osteitis fibrosa cystica. A pathological fracture of the spine compressed the spinal cord, and surgical intervention was required. The neck computed tomography and Tc-99m sestamibi scan showed a solitary parathyroid mass. A minimally invasive parathyroidectomy using intraoperative parathyroid hormone monitoring was performed and two enlarged parathyroid glands identified. This case illustrates the importance of the consideration of a rare brown tumor associated with primary hyperparathyroidism in patients with the bone lesions suggestive of a malignancy. |
topic |
Hyperparathyroidism Osteitis fibrosa cystica Brown tumor |
url |
http://www.e-ceo.org/upload/pdf/ceo-6-110.pdf |
work_keys_str_mv |
AT jahyunlee osteitisfibrosacysticamistakenformalignantdisease AT sungminchung osteitisfibrosacysticamistakenformalignantdisease AT hansukim osteitisfibrosacysticamistakenformalignantdisease |
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