Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenografts.

BACKGROUND:Tumor hypoxia is relevant for tumor growth, metabolism, resistance to chemotherapy and metastasis. We have previously shown that hyperoxia, using hyperbaric oxygen treatment (HBOT), attenuates tumor growth and shifts the phenotype from mesenchymal to epithelial (MET) in the DMBA-induced m...

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Bibliographic Details
Main Authors: Kristine Yttersian Sletta, Maria K Tveitarås, Ning Lu, Agnete S T Engelsen, Rolf K Reed, Annette Garmann-Johnsen, Linda Stuhr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5568407?pdf=render