Unravelling the Regions of Mutant F508del-CFTR More Susceptible to the Action of Four Cystic Fibrosis Correctors

Unravelling the Regions of Mutant F508del-CFTR More Susceptible to the Action of Four Cystic Fibrosis Correctors

Cystic fibrosis (CF) is a genetic disease associated with the defective function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein that causes obstructive disease and chronic bacterial infections in airway epithelia. The most prevalent CF-causing mutation, the deletion of phe...

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Bibliographic Details
Main Authors: Giulia Amico, Chiara Brandas, Oscar Moran, Debora Baroni
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
cystic fibrosis transmembrane conductance regulator (cftr)
cystic fibrosis
f508del-cftr
cftr-correctors
cftr halves
transmembrane-nucleotide binding domains
Online Access:https://www.mdpi.com/1422-0067/20/21/5463

Internet

https://www.mdpi.com/1422-0067/20/21/5463

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