Dilation of Brain Veins and Perivascular Infiltration by Glioblastoma Cells in an In Vivo Assay of Early Tumor Angiogenesis

The cranial window (CW) technique provides a simple and low-cost method to assess tumor angiogenesis in the brain. The CW combined with histology using selective markers for tumor and endothelial cells can allow a sensitive monitoring of novel antiangiogenesis therapies in preclinical models. The CW...

Full description

Bibliographic Details
Main Authors: Quintino Giorgio D’Alessandris, Simone Pacioni, Vittorio Stumpo, Mariachiara Buccarelli, Liverana Lauretti, Martina Giordano, Rina Di Bonaventura, Maurizio Martini, Luigi M. Larocca, Stefano Giannetti, Nicola Montano, Maria Laura Falchetti, Lucia Ricci-Vitiani, Roberto Pallini
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2021/8891045