The lncRNA CASC9 alleviates lipopolysaccharide-induced acute kidney injury by regulating the miR-424-5p/TXNIP pathway

Objective This study aimed to clarify the mechanism by which the long non-coding RNA cancer susceptibility candidate 9 (CASC9) alleviates sepsis-related acute kidney injury (S-AKI). Methods A lipopolysaccharide (LPS)-induced AKI model was established to simulate S-AKI. HK-2 human renal tubular epith...

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Bibliographic Details
Main Authors: Hai-Peng Fan, Zhi-Xia Zhu, Jia-Jun Xu, Yu-Tang Li, Chun-Wen Guo, Hong Yan
Format: Article
Language:English
Published: SAGE Publishing 2021-08-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605211037495