Decline of COPD exacerbations in clinical trials over two decades – a systematic review and meta-regression

Abstract Background An important goal of chronic obstructive pulmonary disease (COPD) treatment is to reduce the frequency of exacerbations. Some observations suggest a decline in exacerbation rates in clinical trials over time. A more systematic understanding would help to improve the design and in...

Full description

Bibliographic Details
Main Authors: Stefan Andreas, Christian Röver, Judith Heinz, Sebastian Straube, Henrik Watz, Tim Friede
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-019-1163-2